Microarray Analysis of Toxicogenomic Effects of Triclosan on Staphylococcus aureus
From ArrayWiki
| PubMed ID: | none |
|---|---|
| Contact: | Hyeung-Jin Jang
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| Species: | Staphylococcus aureus |
| Platform: | Affymetrix GeneChip S. aureus Genome Array |
| Number of Samples: | 15 |
| Date Range: | 05/15/2007 - 06/01/2007 |
| Experiment Quality: | 98.14 3.29 % |
| Link to Repository: | GSE8861 |
| Original Intensity Data: | Download |
| Clean Intensity Data: | Download |
| Original PLIER Data: | Download |
| Clean PLIER Data: | Download |
| Clean CEL Files: | |
| Data Rank: | 
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In the present study, we employed Affymetrix Staphylococcus aureus GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Staphylococcus aureus to triclosan, which involved initial growth inhibition and metabolism.
Design: We conducted five independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of triclosan. We calculated fold change as the ratio between the signal averages of five untreated (control) and five triclosan-treated (experimental) cultures for 0, 10 and 60 min exposures.
Type: Transcriptome study; antimicrobial response; time course
Contents |
[edit] Contributors
- Hyeung-Jin Jang
- Freshteh Toghrol
- William E Bentley
[edit] Protocols
[edit] References
[edit] Links
GEO Accession for this experiment: GSE8861. (Public on Aug 25 2007)
RAW data: tar file.
[edit] Analysis
 Before Normalization |
 After Normalization & Cleaning |
