Gene expression data from sorted IL-7Rhi/lo effector CD8 T cells on day 6/7 after LCMV armstrong infection

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PubMed ID: none
Contact: Susan Kaech

Image:email_GSE8678.png
Yale University

Species: Mus musculus
Platform: Affymetrix GeneChip Mouse Genome 430 2.0 Array
Number of Samples: 6
Date Range: 07/18/2006 - 07/18/2006
Experiment Quality: 98.88
3.25 %
Link to Repository: GSE8678
Original Intensity Data: Download
Clean Intensity Data: Download
Original PLIER Data: Download
Clean PLIER Data: Download
Clean CEL Files:
Data Rank:

At the peak of the CD8 T cell response to acture viral and bacterial infections, expression of the Interleukin-7 Receptor (IL-7R) marks Memory Precursor Effector CD8 T Cells (MPECs) from other Short-Lived Effector CD8 T cells (SLECs), which are IL-7Rlo. This study was designed to determine the gene expression differences between these two subsets of effector CD8 T cells.

Design: This study compared IL-7Rhi and IL-7Rlo LCMV-specific P14 Transgenic CD8 T cells, sorted from LCMV armstrong infected recipient mice 6/7 days after infection. Data includes 3 independent replicates for the IL-7Rhi and IL-7Rlo groups.

Type: expression comparison


Contents

[edit] Contributors

  • Susan M Kaech
  • Nikhil S Joshi

[edit] Protocols

[edit] References

[edit] Links

GEO Accession for this experiment: GSE8678. (Public on Aug 23 2007)

RAW data: tar file.

[edit] Analysis

Gel Plots

Before Normalization

After Normalization & Cleaning

[edit] Samples/Quality Control

Sample Date Scanned Source Link Probe Variance Data Artifact Mask Quality Score
Effector CD8 T cells, IL-7Rlo, rep1 07/18/06 12:10:56 GSM215223 Probe variance for Effector CD8 T cells, IL-7Rlo, rep1 Artifact mask for Effector CD8 T cells, IL-7Rlo, rep1 98.6637
0.1 %
Effector CD8 T cells, IL-7Rlo, rep2 07/18/06 12:20:14 GSM215224 Probe variance for Effector CD8 T cells, IL-7Rlo, rep2 Artifact mask for Effector CD8 T cells, IL-7Rlo, rep2 98.7636
0.25 %
Effector CD8 T cells, IL-7Rlo, rep3 07/18/06 12:29:30 GSM215225 Probe variance for Effector CD8 T cells, IL-7Rlo, rep3 Artifact mask for Effector CD8 T cells, IL-7Rlo, rep3 98.9182
18.18 %
Effector CD8 T cells, IL-7Rhi, rep1 07/18/06 11:43:06 GSM215226 Probe variance for Effector CD8 T cells, IL-7Rhi, rep1 Artifact mask for Effector CD8 T cells, IL-7Rhi, rep1 98.5633
0.16 %
Effector CD8 T cells, IL-7Rhi, rep2 07/18/06 11:52:32 GSM215227 Probe variance for Effector CD8 T cells, IL-7Rhi, rep2 Artifact mask for Effector CD8 T cells, IL-7Rhi, rep2 99.1495
0.03 %
Effector CD8 T cells, IL-7Rhi, rep3 07/18/06 12:01:42 GSM215228 Probe variance for Effector CD8 T cells, IL-7Rhi, rep3 Artifact mask for Effector CD8 T cells, IL-7Rhi, rep3 99.2154
0.77 %
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