Connectivity Map Batch 02 Random Load - CMAP2
From ArrayWiki
| PubMed ID: | 17008526 |
|---|---|
| Contact: | Justin Lamb
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| Species: | homo sapiens (cell lines) |
| Platform: | HT_HG-U133A |
| Number of Samples: | 269 |
| Date Range: | 09/05/2003 - 11/28/2006 |
| Experiment Quality: | 67.64 0.1 % 83.77 |
| Link to Repository: | |
| Original Intensity Data: | Download |
| Clean Intensity Data: | Download |
| Original PLIER Data: | Download |
| Clean PLIER Data: | Download |
| Clean CEL Files: | Download |
| Data Rank: | 
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To pursue a systematic approach to the discovery of functional connections among diseases, genetic perturbation, and drug action, we have created the first installment of a reference collection of gene-expression profiles from cultured human cells treated with bioactive small molecules, together with pattern-matching software to mine these data. We demonstrate that this 'Connectivity Map' resource can be used to find connections among small molecules sharing a mechanism of action, chemicals and physiological processes, and diseases and drugs. These results indicate the feasibility of the approach and suggest the value of a large-scale community Connectivity Map project.
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 Before Normalization |
 After Normalization & Cleaning |
